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CIBCB
2006
IEEE
13 years 10 months ago
Prediction of the Number of Helices for the Twilight Zone Proteins
– Protein structure prediction is one of the core research areas in bioinformatics. This paper addresses the protein secondary structure prediction problem for the twilight zone ...
Kanaka Durga Kedarisetti, Ke Chen, Aashima Kapoor,...
BMCBI
2010
147views more  BMCBI 2010»
13 years 4 months ago
Learning biological network using mutual information and conditional independence
Background: Biological networks offer us a new way to investigate the interactions among different components and address the biological system as a whole. In this paper, a revers...
Dong-Chul Kim, Xiaoyu Wang, Chin-Rang Yang, Jean G...
BIBM
2008
IEEE
217views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
Combining Hierarchical Inference in Ontologies with Heterogeneous Data Sources Improves Gene Function Prediction
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...
BIBE
2009
IEEE
185views Bioinformatics» more  BIBE 2009»
13 years 9 months ago
Anomaly-free Prediction of Gene Ontology Annotations Using Bayesian Networks
Gene and protein structural and functional annotations expressed through controlled terminologies and ontologies are paramount especially for the aim of inferring new biomedical k...
Marco Tagliasacchi, Marco Masseroli
BMCBI
2006
108views more  BMCBI 2006»
13 years 4 months ago
Gene function classification using Bayesian models with hierarchy-based priors
We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic ...
Babak Shahbaba, Radford M. Neal