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BMCBI
2011
13 years 13 days ago
DoBo: Protein domain boundary prediction by integrating evolutionary signals and machine learning
Background: Accurate identification of protein domain boundaries is useful for protein structure determination and prediction. However, predicting protein domain boundaries from a...
Jesse Eickholt, Xin Deng, Jianlin Cheng
BMCBI
2004
123views more  BMCBI 2004»
13 years 5 months ago
Interaction profile-based protein classification of death domain
Background: The increasing number of protein sequences and 3D structure obtained from genomic initiatives is leading many of us to focus on proteomics, and to dedicate our experim...
Drew Lett, Michael Hsing, Frederic Pio
BMCBI
2006
159views more  BMCBI 2006»
13 years 5 months ago
MultiSeq: unifying sequence and structure data for evolutionary analysis
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
Elijah Roberts, John Eargle, Dan Wright, Zaida Lut...
BMCBI
2010
140views more  BMCBI 2010»
13 years 2 months ago
An improved machine learning protocol for the identification of correct Sequest search results
Background: Mass spectrometry has become a standard method by which the proteomic profile of cell or tissue samples is characterized. To fully take advantage of tandem mass spectr...
Morten Kallberg, Hui Lu
IJAR
2008
93views more  IJAR 2008»
13 years 5 months ago
Prototype based fuzzy classification in clinical proteomics
Proteomic profiling based on mass spectrometry is an important tool for studies at the protein and peptide level in medicine and health care. Thereby, the identification of releva...
Frank-Michael Schleif, Thomas Villmann, Barbara Ha...