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» Protein identification as an information retrieval problem
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BMCBI
2010
160views more  BMCBI 2010»
13 years 5 months ago
Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
Young-Rae Cho, Aidong Zhang
BMCBI
2007
149views more  BMCBI 2007»
13 years 5 months ago
SAMPI: Protein Identification with Mass Spectra Alignments
Background: Mass spectrometry based peptide mass fingerprints (PMFs) offer a fast, efficient, and robust method for protein identification. A protein is digested (usually by tryps...
Hans-Michael Kaltenbach, Andreas Wilke, Sebastian ...
BMCBI
2007
151views more  BMCBI 2007»
13 years 5 months ago
Identification of hot regions in protein-protein interactions by sequential pattern mining
Background: Identification of protein interacting sites is an important task in computational molecular biology. As more and more protein sequences are deposited without available...
Chen-Ming Hsu, Chien-Yu Chen, Baw-Jhiune Liu, Chih...
TCBB
2011
13 years 12 days ago
A Partial Set Covering Model for Protein Mixture Identification Using Mass Spectrometry Data
—Protein identification is a key and essential step in mass spectrometry (MS) based proteome research. To date, there are many protein identification strategies that employ eithe...
Zengyou He, Can Yang, Weichuan Yu
ADC
2006
Springer
158views Database» more  ADC 2006»
13 years 11 months ago
Dimensionality reduction in patch-signature based protein structure matching
Searching bio-chemical structures is becoming an important application domain of information retrieval. This paper introduces a protein structure matching problem and formulates i...
Zi Huang, Xiaofang Zhou, Dawei Song, Peter Bruza