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BMCBI
2006
150views more  BMCBI 2006»
13 years 4 months ago
Protein structure similarity from principle component correlation analysis
Background: Owing to rapid expansion of protein structure databases in recent years, methods of structure comparison are becoming increasingly effective and important in revealing...
Xiaobo Zhou, James Chou, Stephen T. C. Wong
BMCBI
2004
150views more  BMCBI 2004»
13 years 4 months ago
Inter-residue distances derived from fold contact propensities correlate with evolutionary substitution costs
Background: The wealth of information on protein structure has led to a variety of statistical analyses of the role played by individual amino acid types in the protein fold. In p...
Gareth Williams, Patrick Doherty
BMCBI
2006
150views more  BMCBI 2006»
13 years 4 months ago
Cluster analysis of protein array results via similarity of Gene Ontology annotation
Background: With the advent of high-throughput proteomic experiments such as arrays of purified proteins comes the need to analyse sets of proteins as an ensemble, as opposed to t...
Cheryl Wolting, C. Jane McGlade, David Tritchler
BMCBI
2004
119views more  BMCBI 2004»
13 years 4 months ago
PASS2: an automated database of protein alignments organised as structural superfamilies
Background: The functional selection and three-dimensional structural constraints of proteins in nature often relates to the retention of significant sequence similarity between p...
Anirban Bhaduri, Ganesan Pugalenthi, Ramanathan So...
BMCBI
2008
170views more  BMCBI 2008»
13 years 4 months ago
Evaluation of GO-based functional similarity measures using S. cerevisiae protein interaction and expression profile data
Background: Researchers interested in analysing the expression patterns of functionally related genes usually hope to improve the accuracy of their results beyond the boundaries o...
Tao Xu, LinFang Du, Yan Zhou