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» Protein-Based Analysis of Alternative Splicing in the Human ...
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BMCBI
2007
115views more  BMCBI 2007»
13 years 4 months ago
SpliceMiner: a high-throughput database implementation of the NCBI Evidence Viewer for microarray splice variant analysis
Background: There are many fewer genes in the human genome than there are expressed transcripts. Alternative splicing is the reason. Alternatively spliced transcripts are often sp...
Ari B. Kahn, Michael C. Ryan, Hongfang Liu, Barry ...
BMCBI
2004
121views more  BMCBI 2004»
13 years 5 months ago
DEDB: a database of Drosophila melanogaster exons in splicing graph form
Background: A wealth of quality genomic and mRNA/EST sequences in recent years has provided the data required for large-scale genome-wide analysis of alternative splicing. We have...
Bernett T. K. Lee, Tin Wee Tan, Shoba Ranganathan
BMCBI
2004
102views more  BMCBI 2004»
13 years 5 months ago
No statistical support for correlation between the positions of protein interaction sites and alternatively spliced regions
Background: Alternative splicing is an efficient mechanism for increasing the variety of functions fulfilled by proteins in a living cell. It has been previously demonstrated that...
Marc N. Offman, Ramil N. Nurtdinov, Mikhail S. Gel...
BMCBI
2008
106views more  BMCBI 2008»
13 years 5 months ago
SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi,
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...