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BMCBI
2004
146views more  BMCBI 2004»
13 years 5 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker
BMCBI
2004
126views more  BMCBI 2004»
13 years 5 months ago
A probabilistic model for the evolution of RNA structure
Background: For the purposes of finding and aligning noncoding RNA gene- and cis-regulatory elements in multiple-genome datasets, it is useful to be able to derive multi-sequence ...
Ian Holmes
JSW
2008
106views more  JSW 2008»
13 years 5 months ago
Hierarchical Image Segmentation by Structural Content
Image quality loss resulting from artifacts depends on the nature and strength of the artifacts as well as the context or background in which they occur. In order to include the im...
Nathir A. Rawashdeh, Shaun T. Love, Kevin D. Donoh...
BMCBI
2006
137views more  BMCBI 2006»
13 years 5 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...