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BMCBI
2006
180views more  BMCBI 2006»
13 years 5 months ago
Building multiclass classifiers for remote homology detection and fold recognition
Motivation Protein remote homology prediction and fold recognition are central problems in computational biology. Supervised learning algorithms based on support vector machines a...
Huzefa Rangwala, George Karypis
BMCBI
2007
144views more  BMCBI 2007»
13 years 5 months ago
Motif kernel generated by genetic programming improves remote homology and fold detection
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
Tony Håndstad, Arne J. H. Hestnes, Pål...
BMCBI
2008
140views more  BMCBI 2008»
13 years 5 months ago
SCPRED: Accurate prediction of protein structural class for sequences of twilight-zone similarity with predicting sequences
Background: Protein structure prediction methods provide accurate results when a homologous protein is predicted, while poorer predictions are obtained in the absence of homologou...
Lukasz A. Kurgan, Krzysztof J. Cios, Ke Chen 0003
TCBB
2008
138views more  TCBB 2008»
13 years 5 months ago
PairProSVM: Protein Subcellular Localization Based on Local Pairwise Profile Alignment and SVM
The subcellular locations of proteins are important functional annotations. An effective and reliable subcellular localization method is necessary for proteomics research. This pap...
Man-Wai Mak, Jian Guo, Sun-Yuan Kung
BMCBI
2008
146views more  BMCBI 2008»
13 years 5 months ago
ProLoc-GO: Utilizing informative Gene Ontology terms for sequence-based prediction of protein subcellular localization
Background: Gene Ontology (GO) annotation, which describes the function of genes and gene products across species, has recently been used to predict protein subcellular and subnuc...
Wen-Lin Huang, Chun-Wei Tung, Shih-Wen Ho, Shiow-F...