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» RIBOWEB: Linking Structural Computations to a Knowledge Base...
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BMCBI
2008
87views more  BMCBI 2008»
13 years 5 months ago
Volume-based solvation models out-perform area-based models in combined studies of wild-type and mutated protein-protein interfa
Background: Empirical binding models have previously been investigated for the energetics of protein complexation (G models) and for the influence of mutations on complexation (i....
Salim Bougouffa, Jim Warwicker
BMCBI
2010
105views more  BMCBI 2010»
13 years 5 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
ATAL
2008
Springer
13 years 7 months ago
A statistical relational model for trust learning
We address the learning of trust based on past observations and context information. We argue that from the truster's point of view trust is best expressed as one of several ...
Achim Rettinger, Matthias Nickles, Volker Tresp