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» RNALogo: a new approach to display structural RNA alignment
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NAR
2008
101views more  NAR 2008»
13 years 3 months ago
RNALogo: a new approach to display structural RNA alignment
Regulatory RNAs play essential roles in many essential biological processes, ranging from gene regulation to protein synthesis. This work presents a web-based tool, RNALogo, to cr...
Tzu-Hao Chang, Jorng-Tzong Horng, Hsien-Da Huang
BIOSURVEILLANCE
2007
Springer
13 years 10 months ago
Detecting Conserved RNA Secondary Structures in Viral Genomes: The RADAR Approach
Abstract. Conserved regions, or motifs, present among RNA secondary structures serve as a useful indicator for predicting the functionality of the RNA molecules. Automated detectio...
Mugdha Khaladkar, Jason T. L. Wang
BMCBI
2008
140views more  BMCBI 2008»
13 years 4 months ago
Improved accuracy of multiple ncRNA alignment by incorporating structural information into a MAFFT-based framework
Background: Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs). Recent studies, mainly based on various approximations ...
Kazutaka Katoh, Hiroyuki Toh
BMCBI
2002
108views more  BMCBI 2002»
13 years 4 months ago
A memory-efficient dynamic programming algorithm for optimal alignment of a sequence to an RNA secondary structure
Background: Covariance models (CMs) are probabilistic models of RNA secondary structure, analogous to profile hidden Markov models of linear sequence. The dynamic programming algo...
Sean R. Eddy
BMCBI
2008
109views more  BMCBI 2008»
13 years 4 months ago
ConStruct: Improved construction of RNA consensus structures
Background: Aligning homologous non-coding RNAs (ncRNAs) correctly in terms of sequence and structure is an unresolved problem, due to both mathematical complexity and imperfect s...
Andreas Wilm, Kornelia Linnenbrink, Gerhard Steger