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TCS
2008
13 years 4 months ago
A small trip in the untranquil world of genomes: A survey on the detection and analysis of genome rearrangement breakpoints
Genomes are dynamic molecules that are constantly undergoing mutations and rearrangements. The latter are large scale changes in a genome organisation that participate in the evol...
Claire Lemaitre, Marie-France Sagot
GCB
2003
Springer
105views Biometrics» more  GCB 2003»
13 years 10 months ago
In silico prediction of UTR repeats using clustered EST data
Clustering of EST data is a method for the non-redundant representation of an organisms transcriptome. During clustering of large amounts of EST data, usually some large clusters ...
Stefan A. Rensing, Daniel Lang, Ralf Reski
BMCBI
2010
148views more  BMCBI 2010»
13 years 5 months ago
Calling SNPs without a reference sequence
Background: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a refere...
Aakrosh Ratan, Yu Zhang, Vanessa M. Hayes, Stephan...
BMCBI
2004
140views more  BMCBI 2004»
13 years 4 months ago
What can we learn from noncoding regions of similarity between genomes?
Background: In addition to known protein-coding genes, large amounts of apparently non-coding sequence are conserved between the human and mouse genomes. It seems reasonable to as...
Thomas A. Down, Tim J. P. Hubbard
BMCBI
2007
247views more  BMCBI 2007»
13 years 4 months ago
A survey of DNA motif finding algorithms
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...
Modan K. Das, Ho-Kwok Dai