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BMCBI
2006
180views more  BMCBI 2006»
13 years 5 months ago
The Gaggle: An open-source software system for integrating bioinformatics software and data sources
Background: Systems biologists work with many kinds of data, from many different sources, using a variety of software tools. Each of these tools typically excels at one type of an...
Paul T. Shannon, David J. Reiss, Richard Bonneau, ...
BMCBI
2006
165views more  BMCBI 2006»
13 years 5 months ago
A stable gene selection in microarray data analysis
Background: Microarray data analysis is notorious for involving a huge number of genes compared to a relatively small number of samples. Gene selection is to detect the most signi...
Kun Yang, Zhipeng Cai, Jianzhong Li, Guohui Lin
BMCBI
2005
121views more  BMCBI 2005»
13 years 5 months ago
Evaluation of gene importance in microarray data based upon probability of selection
Background: Microarray devices permit a genome-scale evaluation of gene function. This technology has catalyzed biomedical research and development in recent years. As many import...
Li M. Fu, Casey S. Fu-Liu
BMCBI
2005
127views more  BMCBI 2005»
13 years 5 months ago
Genomes are covered with ubiquitous 11 bp periodic patterns, the "class A flexible patterns"
Background: The genomes of prokaryotes and lower eukaryotes display a very strong 11 bp periodic bias in the distribution of their nucleotides. This bias is present throughout a g...
Etienne Larsabal, Antoine Danchin
BMCBI
2005
124views more  BMCBI 2005»
13 years 5 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...