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CMSB
2007
Springer
13 years 11 months ago
Reconstructing Metabolic Pathways by Bidirectional Chemical Search
Abstract. One of the main challenges in systems biology is the establishment of the metabolome: a catalogue of the metabolites and biochemical reactions present in a specific orga...
Liliana Félix, Francesc Rosselló, Ga...
BMCBI
2006
135views more  BMCBI 2006»
13 years 4 months ago
Correcting ligands, metabolites, and pathways
Background: A wide range of research areas in bioinformatics, molecular biology and medicinal chemistry require precise chemical structure information about molecules and reaction...
Martin A. Ott, Gert Vriend
BMCBI
2010
191views more  BMCBI 2010»
13 years 4 months ago
BiGG: a Biochemical Genetic and Genomic knowledgebase of large scale metabolic reconstructions
Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
Jan Schellenberger, Junyoung O. Park, Tom M. Conra...
NAR
2008
103views more  NAR 2008»
13 years 4 months ago
STITCH: interaction networks of chemicals and proteins
The knowledge about interactions between proteins and small molecules is essential for the understanding of molecular and cellular functions. However, information on such interact...
Michael Kuhn 0004, Christian von Mering, Monica Ca...
BMCBI
2010
125views more  BMCBI 2010»
13 years 4 months ago
Compartmentalization of the Edinburgh Human Metabolic Network
Background: Direct in vivo investigation of human metabolism is complicated by the distinct metabolic functions of various sub-cellular organelles. Diverse micro-environments in d...
Tong Hao, Hongwu Ma, Xue-Ming Zhao, Igor Goryanin