Understanding the self-regulatory mechanisms controlling the spatial and temporal structure of multicellular organisms represents one of the major challenges in molecular biology. ...
Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental ...
Kyoung Ae Kim, Sabrina L. Spencer, John G. Albeck,...
Chemical Genetic Programming (CGP) is a new method of genetic programming that introduced collision-based biochemical processes and realized dynamic mapping from genotypic strings ...
Wojciech Piaseczny, Hideaki Suzuki, Hidefumi Sawai
Background: Microevolution is the study of short-term changes of alleles within a population and their effects on the phenotype of organisms. The result of the below-species-level...
Background: Gene expression programs depend on recognition of cis elements in promoter region of target genes by transcription factors (TFs), but how TFs regulate gene expression ...