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BMCBI
2010
130views more  BMCBI 2010»
13 years 5 months ago
Amino acid "little Big Bang": Representing amino acid substitution matrices as dot products of Euclidian vectors
Background: Sequence comparisons make use of a one-letter representation for amino acids, the necessary quantitative information being supplied by the substitution matrices. This ...
Karel Zimmermann, Jean-François Gibrat
BMCBI
2010
224views more  BMCBI 2010»
13 years 5 months ago
An adaptive optimal ensemble classifier via bagging and rank aggregation with applications to high dimensional data
Background: Generally speaking, different classifiers tend to work well for certain types of data and conversely, it is usually not known a priori which algorithm will be optimal ...
Susmita Datta, Vasyl Pihur, Somnath Datta
BMCBI
2008
147views more  BMCBI 2008»
13 years 5 months ago
Transmembrane helix prediction using amino acid property features and latent semantic analysis
Background: Prediction of transmembrane (TM) helices by statistical methods suffers from lack of sufficient training data. Current best methods use hundreds or even thousands of f...
Madhavi Ganapathiraju, Narayanas Balakrishnan, Raj...
INFORMS
1998
100views more  INFORMS 1998»
13 years 5 months ago
Feature Selection via Mathematical Programming
The problem of discriminating between two nite point sets in n-dimensional feature space by a separating plane that utilizes as few of the features as possible, is formulated as a...
Paul S. Bradley, Olvi L. Mangasarian, W. Nick Stre...