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» Representation for Discovery of Protein Motifs
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ALMOB
2007
155views more  ALMOB 2007»
13 years 5 months ago
Finding coevolving amino acid residues using row and column weighting of mutual information and multi-dimensional amino acid rep
Background: Some amino acid residues functionally interact with each other. This interaction will result in an evolutionary co-variation between these residues – coevolution. Ou...
Rodrigo Gouveia-Oliveira, Anders Gorm Pedersen
BMCBI
2010
121views more  BMCBI 2010»
13 years 5 months ago
Knowledge-based annotation of small molecule binding sites in proteins
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
Ratna R. Thangudu, Manoj Tyagi, Benjamin A. Shoema...
SSDBM
2006
IEEE
163views Database» more  SSDBM 2006»
13 years 11 months ago
ACache: Using Caching to Improve the Performance of Multiple Sequence Alignments
Multiple sequence alignment represents a class of powerful bioinformatics tools with many uses in computational biology ranging from discovery of characteristic motifs and conserv...
Xun Tu, Kajal T. Claypool, Cindy X. Chen
KDD
2004
ACM
210views Data Mining» more  KDD 2004»
14 years 6 months ago
Visually mining and monitoring massive time series
Moments before the launch of every space vehicle, engineering discipline specialists must make a critical go/no-go decision. The cost of a false positive, allowing a launch in spi...
Jessica Lin, Eamonn J. Keogh, Stefano Lonardi, Jef...
ML
2011
ACM
308views Machine Learning» more  ML 2011»
13 years 7 days ago
Relational information gain
Abstract. Type Extension Trees (TET) have been recently introduced as an expressive representation language allowing to encode complex combinatorial features of relational entities...
Marco Lippi, Manfred Jaeger, Paolo Frasconi, Andre...