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ICASSP
2011
IEEE
12 years 9 months ago
Non-stationary noise estimation method based on bias-residual component decomposition for robust speech recognition
This paper addresses a noise suppression problem, namely the estimation of non-stationary noise sequences. In this problem, we assume that non-stationary noise can be decomposed i...
Masakiyo Fujimoto, Shinji Watanabe, Tomohiro Nakat...
BMCBI
2008
84views more  BMCBI 2008»
13 years 5 months ago
Prediction of specificity-determining residues for small-molecule kinase inhibitors
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
Daniel R. Caffrey, Elizabeth A. Lunney, Deborah J....
BMCBI
2008
134views more  BMCBI 2008»
13 years 5 months ago
Prediction of protein-protein binding site by using core interface residue and support vector machine
Background: The prediction of protein-protein binding site can provide structural annotation to the protein interaction data from proteomics studies. This is very important for th...
Nan Li, Zhonghua Sun, Fan Jiang
TCBB
2008
107views more  TCBB 2008»
13 years 5 months ago
Coclustering of Human Cancer Microarrays Using Minimum Sum-Squared Residue Coclustering
It is a consensus in microarray analysis that identifying potential local patterns, characterized by coherent groups of genes and conditions, may shed light on the discovery of pre...
Hyuk Cho, Inderjit S. Dhillon
BMCBI
2010
86views more  BMCBI 2010»
13 years 5 months ago
Protein binding hot spots and the residue-residue pairing preference: a water exclusion perspective
Background: A protein binding hot spot is a small cluster of residues tightly packed at the center of the interface between two interacting proteins. Though a hot spot constitutes...
Qian Liu, Jinyan Li