The study of non-sequential alignments, with different connectivity of the aligned fragments in the proteins being compared can offer a more complete picture of the structural, evo...
We introduce a method for comparing protein structures using the notion of residue contexts based on protein Cα-atom backbones. The residue context is derived from the set of vec...
ATP is a ubiquitous nucleotide that provides energy for cellular activities, catalyzes chemical reactions, and is involved in cellular signaling. The knowledge of the ATPprotein in...
Ke Chen 0003, Marcin J. Mizianty, Lukasz A. Kurgan
PAR-3D (http://sunserver.cdfd.org.in:8080/protease /PAR_3D/index.html) is a web-based tool that exploits the fact that relative juxtaposition of active site residues is a conserve...
Background: The dynamic motions of many proteins are central to their function. It therefore follows that the dynamic requirements of a protein are evolutionary constrained. In or...