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BMCBI
2005
108views more  BMCBI 2005»
13 years 4 months ago
SplitTester: software to identify domains responsible for functional divergence in protein family
Background: Many protein families have undergone functional divergence after gene duplications such that current subgroups of the family carry out overlapping but distinct biologi...
Xiang Gao, Kent Vander Velden, Daniel F. Voytas, X...
BMCBI
2005
167views more  BMCBI 2005»
13 years 4 months ago
Cross-platform analysis of cancer microarray data improves gene expression based classification of phenotypes
Background: The extensive use of DNA microarray technology in the characterization of the cell transcriptome is leading to an ever increasing amount of microarray data from cancer...
Patrick Warnat, Roland Eils, Benedikt Brors
AI
2002
Springer
13 years 4 months ago
Ensembling neural networks: Many could be better than all
Neural network ensemble is a learning paradigm where many neural networks are jointly used to solve a problem. In this paper, the relationship between the ensemble and its compone...
Zhi-Hua Zhou, Jianxin Wu, Wei Tang
BMCBI
2004
114views more  BMCBI 2004»
13 years 4 months ago
Extending the mutual information measure to rank inferred literature relationships
Background: Within the peer-reviewed literature, associations between two things are not always recognized until commonalities between them become apparent. These commonalities ca...
Jonathan D. Wren
BMCBI
2010
160views more  BMCBI 2010»
13 years 4 months ago
Annotation of gene promoters by integrative data-mining of ChIP-seq Pol-II enrichment data
Background: Use of alternative gene promoters that drive widespread cell-type, tissue-type or developmental gene regulation in mammalian genomes is a common phenomenon. Chromatin ...
Ravi Gupta, Priyankara Wikramasinghe, Anirban Bhat...