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BMCBI
2005
93views more  BMCBI 2005»
13 years 5 months ago
Multiple sequence alignment accuracy and evolutionary distance estimation
Background: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pai...
Michael S. Rosenberg
CANDC
2005
ACM
13 years 5 months ago
MSAID: multiple sequence alignment based on a measure of information discrepancy
We propose an algorithm of global multiple sequence alignment that is based on a measure of what we call information discrepancy. The algorithm follows a progressive alignment ite...
Min Zhang, Weiwu Fang, Junhua Zhang, Zhongxian Chi
AAAI
2004
13 years 6 months ago
PROBCONS: Probabilistic Consistency-Based Multiple Alignment of Amino Acid Sequences
Obtaining an accurate multiple alignment of protein sequences is a difficult computational problem for which many heuristic techniques sacrifice optimality to achieve reasonable r...
Chuong B. Do, Michael Brudno, Serafim Batzoglou
BMCBI
2004
196views more  BMCBI 2004»
13 years 5 months ago
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
Background: In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUS...
Robert C. Edgar
IPPS
2002
IEEE
13 years 10 months ago
Improving Performance of Multiple Sequence Alignment Analysis in Multi-Client Environments
This paper is concerned with the efficient execution of multiplesequence alignmentmethodsin a multipleclientenvironment. Multiple sequence alignment (MSA) is a computationally ex...
Ümit V. Çatalyürek, Eric Stahlber...