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BMCBI
2007
97views more  BMCBI 2007»
13 years 5 months ago
A procedure for the estimation over time of metabolic fluxes in scenarios where measurements are uncertain and/or insufficient
Background: An indirect approach is usually used to estimate the metabolic fluxes of an organism: couple the available measurements with known biological constraints (e.g. stoichi...
Francisco Llaneras, Jesús Picó
BMCBI
2007
114views more  BMCBI 2007»
13 years 5 months ago
Large scale statistical inference of signaling pathways from RNAi and microarray data
Background: The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray tec...
Holger Fröhlich, Mark Fellmann, Holger Sü...
BMCBI
2008
102views more  BMCBI 2008»
13 years 5 months ago
Stability of the core domain of p53: insights from computer simulations
: The tumour suppressor protein p53 protein has a core domain that binds DNA and is the site for most oncogenic mutations. This domain is quite unstable compared to its homologs p...
Arumugam Madhumalar, Derek John Smith, Chandra Ver...
CGF
2005
111views more  CGF 2005»
13 years 4 months ago
Hierarchyless Simplification, Stripification and Compression of Triangulated Two Manifolds
In this paper we explore the algorithmic space in which stripification, simplification and geometric compression of triangulated 2-manifolds overlap. Edge-collase/uncollapse based...
Pablo Diaz-Gutierrez, Meenakshisundaram Gopi, Rena...