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BMCBI
2007
142views more  BMCBI 2007»
13 years 3 months ago
SABERTOOTH: protein structural alignment based on a vectorial structure representation
Background: The task of computing highly accurate structural alignments of proteins in very short computation time is still challenging. This is partly due to the complexity of pr...
Florian Teichert, Ugo Bastolla, Markus Porto
BMCBI
2010
189views more  BMCBI 2010»
13 years 3 months ago
High quality protein sequence alignment by combining structural profile prediction and profile alignment using SABERTOOTH
Background: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become...
Florian Teichert, Jonas Minning, Ugo Bastolla, Mar...
ISMB
1997
13 years 5 months ago
Hierarchical Protein Structure Superposition Using Both Secondary Structure and Atomic Representations
The structural comparison of proteins has become increasingly important as a means to identify protein motifs and fold families. In this paper we present a new algorithm for the c...
Amit Pal Singh, Douglas L. Brutlag
BMCBI
2005
119views more  BMCBI 2005»
13 years 3 months ago
The distance-profile representation and its application to detection of distantly related protein families
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Chin-Jen Ku, Golan Yona
CIKM
2009
Springer
13 years 10 months ago
Linear predictive coding representation of correlated mutation for protein sequence alignment
Background: Although both conservation and correlated mutation (CM) are important information reflecting the different sorts of context in multiple sequence alignment, most of ali...
Chan-seok Jeong, Dongsup Kim