Background: Although homology-based methods are among the most widely used methods for predicting the structure and function of proteins, the question as to whether interface sequ...
Background: Structural properties of proteins such as secondary structure and solvent accessibility contribute to three-dimensional structure prediction, not only in the ab initio...
Gianluca Pollastri, Alberto J. M. Martin, Catherin...
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Metal-binding proteins play important roles in structural stability, signaling, regulation, transport, immune response, metabolism control, and metal homeostasis. Because of their...
H. H. Lin, L. Y. Han, H. L. Zhang, C. J. Zheng, B....
Background: Intrinsically disordered proteins play important roles in various cellular activities and their prevalence was implicated in a number of human diseases. The knowledge ...
Marcin J. Mizianty, Tuo Zhang, Bin Xue, Yaoqi Zhou...