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» SIMAGE: simulation of DNA-microarray gene expression data
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JCB
2007
198views more  JCB 2007»
13 years 5 months ago
Bayesian Hierarchical Model for Large-Scale Covariance Matrix Estimation
Many bioinformatics problems can implicitly depend on estimating large-scale covariance matrix. The traditional approaches tend to give rise to high variance and low accuracy esti...
Dongxiao Zhu, Alfred O. Hero III
BMCBI
2007
141views more  BMCBI 2007»
13 years 5 months ago
HeliCis: a DNA motif discovery tool for colocalized motif pairs with periodic spacing
Background: Correct temporal and spatial gene expression during metazoan development relies on combinatorial interactions between different transcription factors. As a consequence...
Erik Larsson, Per Lindahl, Petter Mostad
CDC
2009
IEEE
179views Control Systems» more  CDC 2009»
13 years 10 months ago
Bayesian network approach to understand regulation of biological processes in cyanobacteria
— Bayesian networks have extensively been used in numerous fields including artificial intelligence, decision theory and control. Its ability to utilize noisy and missing data ...
Thanura R. Elvitigala, Abhay K. Singh, Himadri B. ...
BMCBI
2010
94views more  BMCBI 2010»
13 years 5 months ago
Comparison study of microarray meta-analysis methods
Background: Meta-analysis methods exist for combining multiple microarray datasets. However, there are a wide range of issues associated with microarray meta-analysis and a limite...
Anna Campain, Yee Hwa Yang
BMCBI
2005
122views more  BMCBI 2005»
13 years 5 months ago
A microarray data-based semi-kinetic method for predicting quantitative dynamics of genetic networks
Background: Elucidating the dynamic behaviour of genetic regulatory networks is one of the most significant challenges in systems biology. However, conventional quantitative predi...
Katsuyuki Yugi, Yoichi Nakayama, Shigen Kojima, To...