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» SPdb - a signal peptide database
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BMCBI
2005
93views more  BMCBI 2005»
13 years 4 months ago
SPdb - a signal peptide database
Background: The signal peptide plays an important role in protein targeting and protein translocation in both prokaryotic and eukaryotic cells. This transient, short peptide seque...
Khar Heng Choo, Tin Wee Tan, Shoba Ranganathan
EVOW
2010
Springer
13 years 11 months ago
A Local Search Appproach for Transmembrane Segment and Signal Peptide Discrimination
Discriminating between secreted and membrane proteins is a challenging task. This is particularly true for discriminating between transmembrane segments and signal peptides because...
Sami Laroum, Dominique Tessier, Béatrice Du...
ICASSP
2007
IEEE
13 years 11 months ago
Evolutionary Sequence Modeling for Discovery of Peptide Hormones
There are currently a large number of ‘‘orphan’’ G-protein-coupled receptors (GPCRs) whose endogenous ligands (peptide hormones) are unknown. Identification of these pepti...
M. Kemal Sönmez, Lawrence Toll, Nina Zaveri
NAR
2011
222views Computer Vision» more  NAR 2011»
12 years 7 months ago
Effective - a database of predicted secreted bacterial proteins
Protein secretion is a key virulence mechanism of pathogenic and symbiotic bacteria, which makes the investigation of secreted proteins (‘effectors’) crucial for understanding...
Marc-André Jehl, Roland Arnold, Thomas Ratt...
BMCBI
2010
124views more  BMCBI 2010»
13 years 5 months ago
A Dynamic Noise Level Algorithm for Spectral Screening of Peptide MS/MS Spectra
Background: High-throughput shotgun proteomics data contain a significant number of spectra from non-peptide ions or spectra of too poor quality to obtain highly confident peptide...
Hua Xu, Michael A. Freitas