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GECCO
2005
Springer
129views Optimization» more  GECCO 2005»
13 years 10 months ago
Search space modulation in genetic algorithms: evolving the search space by sinusoidal transformations
An experimental form of Modulation (Reinterpretation) of the Search Space is presented. This modulation is developed as a mathematical method that can be implemented directly into...
José Antonio Martin H.
BMCBI
2007
149views more  BMCBI 2007»
13 years 5 months ago
Identification of tissue-specific cis-regulatory modules based on interactions between transcription factors
Background: Evolutionary conservation has been used successfully to help identify cis-acting DNA regions that are important in regulating tissue-specific gene expression. Motivate...
Xueping Yu, Jimmy J. Lin, Donald J. Zack, Jiang Qi...
BMCBI
2007
99views more  BMCBI 2007»
13 years 5 months ago
Statistical significance of cis-regulatory modules
Background: It is becoming increasingly important for researchers to be able to scan through large genomic regions for transcription factor binding sites or clusters of binding si...
Dustin E. Schones, Andrew D. Smith, Michael Q. Zha...
BMCBI
2007
136views more  BMCBI 2007»
13 years 5 months ago
Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
Xiaoyu Chen, Mathieu Blanchette
CEC
2011
IEEE
12 years 5 months ago
Inferring transcriptional regulators for sets of co-expressed genes by multi-objective evolutionary optimization
Abstract—Higher organisms are able to respond to continuously changing external conditions by transducing cellular signals into specific regulatory programs, which control gene ...
Adrian Schröder, Clemens Wrzodek, Johannes Wo...