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» Searching on the Secondary Structure of Protein Sequences
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VLDB
2002
ACM
83views Database» more  VLDB 2002»
13 years 3 months ago
Searching on the Secondary Structure of Protein Sequences
In spite of the many decades of progress in database research, surprisingly scientists in the life sciences community still struggle with inefficient and awkward tools for queryin...
Laurie Hammel, Jignesh M. Patel
DMKD
2003
ACM
110views Data Mining» more  DMKD 2003»
13 years 9 months ago
Weave amino acid sequences for protein secondary structure prediction
Given a known protein sequence, predicting its secondary structure can help understand its three-dimensional (tertiary) structure, i.e., the folding. In this paper, we present an ...
Xiaochun Yang, Bin Wang
BMCBI
2002
108views more  BMCBI 2002»
13 years 4 months ago
A memory-efficient dynamic programming algorithm for optimal alignment of a sequence to an RNA secondary structure
Background: Covariance models (CMs) are probabilistic models of RNA secondary structure, analogous to profile hidden Markov models of linear sequence. The dynamic programming algo...
Sean R. Eddy
BMCBI
2006
137views more  BMCBI 2006»
13 years 4 months ago
Improving the accuracy of protein secondary structure prediction using structural alignment
Background: The accuracy of protein secondary structure prediction has steadily improved over the past 30 years. Now many secondary structure prediction methods routinely achieve ...
Scott Montgomerie, Shan Sundararaj, Warren J. Gall...
NAR
2007
153views more  NAR 2007»
13 years 3 months ago
PROMALS web server for accurate multiple protein sequence alignments
Multiple sequence alignments are essential in homology inference, structure modeling, functional prediction and phylogenetic analysis. We developed a web server that constructs mu...
Jimin Pei, Bong-Hyun Kim, Ming Tang, Nick V. Grish...