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BMCBI
2005
120views more  BMCBI 2005»
13 years 4 months ago
SpectralNET - an application for spectral graph analysis and visualization
Background: Graph theory provides a computational framework for modeling a variety of datasets including those emerging from genomics, proteomics, and chemical genetics. Networks ...
Joshua J. Forman, Paul A. Clemons, Stuart L. Schre...
BMCBI
2008
123views more  BMCBI 2008»
13 years 4 months ago
Functional module detection by functional flow pattern mining in protein interaction networks
eraction networks. In this abstract, we extend this approach by mining functional flow patterns for the purpose of detecting small-sized modules for specific functions. Methods Our...
Young-Rae Cho, Lei Shi, Aidong Zhang
BMCBI
2010
190views more  BMCBI 2010»
13 years 4 months ago
APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Jun-Feng Xia, Xing-Ming Zhao, Jiangning Song, De-S...
CGF
2008
151views more  CGF 2008»
13 years 4 months ago
Navigation and Exploration of Interconnected Pathways
Visualizing pathways, i. e. models of cellular functional networks, is a challenging task in computer assisted biomedicine. Pathways are represented as large collections of interw...
Marc Streit, Michael Kalkusch, Karl Kashofer, Diet...