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BMCBI
2008
108views more  BMCBI 2008»
13 years 5 months ago
New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic backgroun
Background: Few genetic factors predisposing to the sporadic form of amyotrophic lateral sclerosis (ALS) have been identified, but the pathology itself seems to be a true multifac...
Silvana Penco, Massimo Buscema, Maria Cristina Pat...
SIGIR
2008
ACM
13 years 4 months ago
Learning from labeled features using generalized expectation criteria
It is difficult to apply machine learning to new domains because often we lack labeled problem instances. In this paper, we provide a solution to this problem that leverages domai...
Gregory Druck, Gideon S. Mann, Andrew McCallum
BMCBI
2008
98views more  BMCBI 2008»
13 years 5 months ago
MTAP: The Motif Tool Assessment Platform
Background: In recent years, substantial effort has been applied to de novo regulatory motif discovery. At this time, more than 150 software tools exist to detect regulatory bindi...
Daniel Quest, Kathryn Dempsey, Mohammad Shafiullah...
BMCBI
2008
110views more  BMCBI 2008»
13 years 5 months ago
Determining significance of pairwise co-occurrences of events in bursty sequences
Background: Event sequences where different types of events often occur close together arise, e.g., when studying potential transcription factor binding sites (TFBS, events) of ce...
Niina Haiminen, Heikki Mannila, Evimaria Terzi
BMCBI
2008
92views more  BMCBI 2008»
13 years 5 months ago
Proteochemometric modeling of HIV protease susceptibility
Background: A major obstacle in treatment of HIV is the ability of the virus to mutate rapidly into drug-resistant variants. A method for predicting the susceptibility of mutated ...
Maris Lapinsh, Martin Eklund, Ola Spjuth, Peteris ...