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ICASSP
2008
IEEE
13 years 11 months ago
Probabilistic framework for gene expression clustering validation based on gene ontology and graph theory
Based on the correlation between expression and ontologydriven gene similarity, we incorporate functional annotations into gene expression clustering validation. A probabilistic f...
Yinyin Yuan, Chang-Tsun Li
BMCBI
2006
249views more  BMCBI 2006»
13 years 5 months ago
Gene functional similarity search tool (GFSST)
Background: With the completion of the genome sequences of human, mouse, and other species and the advent of high throughput functional genomic research technologies such as biomi...
Peisen Zhang, Jinghui Zhang, Huitao Sheng, James J...
BMCBI
2008
170views more  BMCBI 2008»
13 years 5 months ago
Evaluation of GO-based functional similarity measures using S. cerevisiae protein interaction and expression profile data
Background: Researchers interested in analysing the expression patterns of functionally related genes usually hope to improve the accuracy of their results beyond the boundaries o...
Tao Xu, LinFang Du, Yan Zhou
BMCBI
2007
168views more  BMCBI 2007»
13 years 5 months ago
GOSim - an R-package for computation of information theoretic GO similarities between terms and gene products
Background: With the increased availability of high throughput data, such as DNA microarray data, researchers are capable of producing large amounts of biological data. During the...
Holger Fröhlich, Nora Speer, Annemarie Poustk...
BMCBI
2005
156views more  BMCBI 2005»
13 years 5 months ago
DynGO: a tool for visualizing and mining of Gene Ontology and its associations
Background: A large volume of data and information about genes and gene products has been stored in various molecular biology databases. A major challenge for knowledge discovery ...
Hongfang Liu, Zhang-Zhi Hu, Cathy H. Wu