151 search results - page 1 / 31 » Sequence variation in ligand binding sites in proteins |
BMCBI
2005
13 years 4 months ago
2005
Background: The recent explosion in the availability of complete genome sequences has led to the cataloging of tens of thousands of new proteins and putative proteins. Many of the...
BMCBI
2010
13 years 4 months ago
2010
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...
ISVC
2007
Springer
13 years 11 months ago
2007
Springer
Abstract. The function of a protein is dependent on whether and how it can interact with various ligands. Therefore, an accurate prediction of protein-ligand interactions is paramo...
BMCBI
2006
13 years 4 months ago
2006
Background: Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule bindi...
NIPS
2008
13 years 6 months ago
2008
Metal binding is important for the structural and functional characterization of proteins. Previous prediction efforts have only focused on bonding state, i.e. deciding which prot...