In this paper some of the most fundamental problems in computational biology are proved intractable. The following problems are shown NP-hard for all binary or larger alphabets und...
Abstract. In the context of non-coding RNA (ncRNA) multiple structural alignment, Davydov and Batzoglou introduced in [7] the problem of finding the largest nested linear graph tha...
A common task in biological research is to predict function for proteins by comparing sequences between proteins of known and unknown function. This is often done using pair-wise ...
Advances in modern technologies for measuring protein-protein interaction (PPI) has boosted research in PPI networks analysis and comparison. One of the challenging problems in com...
Identification of Transcription Factor Binding Site (TFBS) motifs in multiple DNA upstream sequences is important in understanding the mechanism of gene regulation. This identific...