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BMCBI
2011
10 years 8 months ago
Simulated evolution applied to study the genetic code optimality using a model of codon reassignments
Background: As the canonical code is not universal, different theories about its origin and organization have appeared. The optimization or level of adaptation of the canonical ge...
Jose Santos, Ángel Monteagudo
BMCBI
2010
138views more  BMCBI 2010»
11 years 1 months ago
A model-independent approach to infer hierarchical codon substitution dynamics
Background: Codon substitution constitutes a fundamental process in molecular biology that has been studied extensively. However, prior studies rely on various assumptions, e.g. r...
Olof Görnerup, Martin Nilsson Jacobi
BMCBI
2007
152views more  BMCBI 2007»
11 years 1 months ago
Recodon: Coalescent simulation of coding DNA sequences with recombination, migration and demography
Background: Coalescent simulations have proven very useful in many population genetics studies. In order to arrive to meaningful conclusions, it is important that these simulation...
Miguel Arenas, David Posada
CIBCB
2007
IEEE
11 years 3 months ago
Optimization of Bacterial Strains with Variable-Sized Evolutionary Algorithms
—In metabolic engineering it is difficult to identify which set of genetic manipulations will result in a microbial strain that achieves a desired production goal, due to the co...
Miguel Rocha, José P. Pinto, Isabel Rocha, ...
RECOMB
2002
Springer
12 years 1 months ago
Comparison of minisatellites
In the class of repeated sequences that occur in DNA, minisatellites have been found polymorphic and became useful tools in genetic mapping and forensic studies. They consist of a...
Eric Rivals, Sèverine Bérard
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