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BMCBI
2008
159views more  BMCBI 2008»
13 years 5 months ago
Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via log
Background: Growing interest on biological pathways has called for new statistical methods for modeling and testing a genetic pathway effect on a health outcome. The fact that gen...
Dawei Liu, Debashis Ghosh, Xihong Lin
FM
2009
Springer
138views Formal Methods» more  FM 2009»
13 years 11 months ago
What Can Formal Methods Bring to Systems Biology?
This position paper argues that the operational modelling approaches from the formal methods community can be applied fruitfully within the systems biology domain. The results can ...
Nicola Bonzanni, K. Anton Feenstra, Wan Fokkink, E...
QEST
2010
IEEE
13 years 2 months ago
Transient Analysis of Generalised Semi-Markov Processes Using Transient Stochastic State Classes
The method of stochastic state classes approaches the analysis of Generalised Semi Markov Processes (GSMP) through symbolic derivation of probability density functions over Differe...
András Horváth, Lorenzo Ridi, Enrico...
BMCBI
2006
179views more  BMCBI 2006»
13 years 4 months ago
Multiscale Hy3S: Hybrid stochastic simulation for supercomputers
Background: Stochastic simulation has become a useful tool to both study natural biological systems and design new synthetic ones. By capturing the intrinsic molecular fluctuation...
Howard Salis, Vassilios Sotiropoulos, Yiannis N. K...