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» Simulating the Hallmarks of Cancer
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ALIFE
2006
13 years 4 months ago
Simulating the Hallmarks of Cancer
Cancer can be viewed as the loss of cooperative cell behaviors that normally facilitate multicellularity, including the formation of tissues and organs. Hanahan and Weinberg descri...
Robert G. Abbott, Stephanie Forrest, Kenneth J. Pi...
IJCBDD
2011
112views more  IJCBDD 2011»
12 years 11 months ago
A novel network model identified a 13-gene lung cancer prognostic signature
: This study presents a novel network methodology to identify prognostic gene signatures. Implication networks based on prediction logic are used to construct genome-wide coexpress...
Nancy Lan Guo, Ying-Wooi Wan, Swetha Bose, James D...
BIBM
2010
IEEE
173views Bioinformatics» more  BIBM 2010»
13 years 1 months ago
Network-based identification of smoking-associated gene signature for lung cancer
This study presents a novel computational approach to identifying a smoking-associated gene signature. The methodology contains the following steps: 1) identifying genes significa...
Ying-Wooi Wan, Changchang Xiao, Nancy Lan Guo
RECOMB
2008
Springer
14 years 4 months ago
Sorting Cancer Karyotypes by Elementary Operations
Since the discovery of the "Philadelphia chromosome" in chronic myelogenous leukemia in 1960, there is an ongoing intensive research of chromosomal aberrations in cancer....
Michal Ozery-Flato, Ron Shamir
BCB
2010
127views Bioinformatics» more  BCB 2010»
12 years 11 months ago
A novel network model for molecular prognosis
Network-based genome-wide association studies (NWAS) utilize the molecular interactions between genes and functional pathways in biomarker identification. This study presents a no...
Ying-Wooi Wan, Swetha Bose, James Denvir, Nancy La...