In this paper we model and simulate a biological system describing the evolution of cancer stem cells into tumors. Starting from some basic hypotheses about the behavior of these ...
Cancer is an evolutionary process; mutated cells are selected for abnormal growth and survivability. Here, a computer simulation is used to model ductal carcinoma in situ (DCIS), ...
We present a method for identifying connected gene subnetworks significantly enriched for genes that are dysregulated in specimens of a disease. These subnetworks provide a signat...
In recent years many experimental investigations have been carried out on vasculogenesis and angiogenesis, the mechanisms of blood vessels formation. Neovascularization is a hallm...
Fabrizio Lamberti, Andrea Gamba, Bartolomeo Montru...
Although there are various types of cancer treatments, none of these currently take into account the effect of ageing of the immune system and hence altered responses to cancer. R...