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» Simulating the Hallmarks of Cancer
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ICASSP
2011
IEEE
12 years 8 months ago
A stochastic compartmental approach to modeling and simulation of cancer spheroid formation and evolution
In this paper we model and simulate a biological system describing the evolution of cancer stem cells into tumors. Starting from some basic hypotheses about the behavior of these ...
Mónica F. Bugallo, Shishir Dash, Galina Bot...
GPEM
2007
116views more  GPEM 2007»
13 years 4 months ago
Using evolvable genetic cellular automata to model breast cancer
Cancer is an evolutionary process; mutated cells are selected for abnormal growth and survivability. Here, a computer simulation is used to model ductal carcinoma in situ (DCIS), ...
Armand Bankhead, Robert B. Heckendorn
RECOMB
2008
Springer
14 years 4 months ago
Detecting Disease-Specific Dysregulated Pathways Via Analysis of Clinical Expression Profiles
We present a method for identifying connected gene subnetworks significantly enriched for genes that are dysregulated in specimens of a disease. These subnetworks provide a signat...
Igor Ulitsky, Richard M. Karp, Ron Shamir
WSCG
2004
168views more  WSCG 2004»
13 years 5 months ago
Computer-assisted Analysis of in-vitro Vasculogenesis and Angiogenesis Processes
In recent years many experimental investigations have been carried out on vasculogenesis and angiogenesis, the mechanisms of blood vessels formation. Neovascularization is a hallm...
Fabrizio Lamberti, Andrea Gamba, Bartolomeo Montru...
ICARIS
2010
Springer
13 years 5 months ago
Defining a Simulation Strategy for Cancer Immunocompetence
Although there are various types of cancer treatments, none of these currently take into account the effect of ageing of the immune system and hence altered responses to cancer. R...
Grazziela P. Figueredo, Uwe Aickelin