67 search results - page 13 / 14 » Simultaneous Alignment and Folding of Protein Sequences |
BMCBI
2010
13 years 5 months ago
2010
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
BMCBI
2006
13 years 5 months ago
2006
Background: The development and testing of functions for the modeling of protein energetics is an important part of current research aimed at understanding protein structure and f...
BMCBI
2005
13 years 5 months ago
2005
Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...
BMCBI
2005
13 years 5 months ago
2005
Background: Secondary structure is used in hierarchical classification of protein structures, identification of protein features, such as helix caps and loops, for fold recognitio...
BMCBI
2004
13 years 5 months ago
2004
Background: Eukaryotic whole genome sequences are accumulating at an impressive rate. Effective methods for comparing multiple whole eukaryotic genomes on a large scale are needed...