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» Somatic evolution of cancer
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GPEM
2007
116views more  GPEM 2007»
13 years 5 months ago
Using evolvable genetic cellular automata to model breast cancer
Cancer is an evolutionary process; mutated cells are selected for abnormal growth and survivability. Here, a computer simulation is used to model ductal carcinoma in situ (DCIS), ...
Armand Bankhead, Robert B. Heckendorn
BMCBI
2002
95views more  BMCBI 2002»
13 years 5 months ago
The functional importance of disease-associated mutation
Background: For many years, scientists believed that point mutations in genes are the genetic switches for somatic and inherited diseases such as cystic fibrosis, phenylketonuria ...
Sean D. Mooney, Teri E. Klein
AIME
2001
Springer
13 years 10 months ago
NasoNet, Joining Bayesian Networks and Time to Model Nasopharyngeal Cancer Spread
Abstract. Cancer spread is a non-deterministic dynamic process. As a consequence, the design of an assistant system for the diagnosis and prognosis of the extent of a cancer should...
Severino F. Galán, Francisco Aguado, Franci...
GECCO
2007
Springer
179views Optimization» more  GECCO 2007»
13 years 12 months ago
Evolutionary selection of minimum number of features for classification of gene expression data using genetic algorithms
Selecting the most relevant factors from genetic profiles that can optimally characterize cellular states is of crucial importance in identifying complex disease genes and biomark...
Alper Küçükural, Reyyan Yeniterzi...
PROCEDIA
2010
120views more  PROCEDIA 2010»
13 years 16 days ago
A coupled convection-diffusion level set model for tracking epithelial cells in colonic crypts
Colorectal cancer is initiated in colonic crypts as a consequence of alterations leading to the disruption of the normal colonic cellular process. We propose a model, which couple...
Isabel N. Figueiredo, Carlos F. Leal, Tommaso Leon...