Cancer is an evolutionary process; mutated cells are selected for abnormal growth and survivability. Here, a computer simulation is used to model ductal carcinoma in situ (DCIS), ...
Background: For many years, scientists believed that point mutations in genes are the genetic switches for somatic and inherited diseases such as cystic fibrosis, phenylketonuria ...
Abstract. Cancer spread is a non-deterministic dynamic process. As a consequence, the design of an assistant system for the diagnosis and prognosis of the extent of a cancer should...
Selecting the most relevant factors from genetic profiles that can optimally characterize cellular states is of crucial importance in identifying complex disease genes and biomark...
Colorectal cancer is initiated in colonic crypts as a consequence of alterations leading to the disruption of the normal colonic cellular process. We propose a model, which couple...
Isabel N. Figueiredo, Carlos F. Leal, Tommaso Leon...