29 search results - page 2 / 6 » Sources of variation in Affymetrix microarray experiments |
BMCBI
2006
13 years 5 months ago
2006
Background: Intensity values measured by Affymetrix microarrays have to be both normalized, to be able to compare different microarrays by removing non-biological variation, and s...
BMCBI
2007
13 years 5 months ago
2007
Background: Affymetrix GeneChips are a popular platform for performing whole-genome experiments on the transcriptome. There are a range of different calibration steps, and users a...
BMCBI
2006
13 years 5 months ago
2006
Background: Gene expression microarray data is notoriously subject to high signal variability. Moreover, unavoidable variation in the concentration of transcripts applied to micro...
BMCBI
2007
13 years 5 months ago
2007
Background: Clustering is an important analysis performed on microarray gene expression data since it groups genes which have similar expression patterns and enables the explorati...
BMCBI
2007
13 years 5 months ago
2007
Background: Genomic deletions and duplications are important in the pathogenesis of diseases, such as cancer and mental retardation, and have recently been shown to occur frequent...