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BMCBI
2008
200views more  BMCBI 2008»
13 years 6 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
ICASSP
2008
IEEE
14 years 15 days ago
Probabilistic framework for gene expression clustering validation based on gene ontology and graph theory
Based on the correlation between expression and ontologydriven gene similarity, we incorporate functional annotations into gene expression clustering validation. A probabilistic f...
Yinyin Yuan, Chang-Tsun Li
BMCBI
2010
105views more  BMCBI 2010»
13 years 6 months ago
The Neural/Immune Gene Ontology: clipping the Gene Ontology for neurological and immunological systems
Background: The Gene Ontology (GO) is used to describe genes and gene products from many organisms. When used for functional annotation of microarray data, GO is often slimmed by ...
Nophar Geifman, Alon Monsonego, Eitan Rubin
NAR
2008
175views more  NAR 2008»
13 years 6 months ago
Onto-CC: a web server for identifying Gene Ontology conceptual clusters
The Gene Ontology (GO) vocabulary has been extensively explored to analyze the functions of coexpressed genes. However, despite its extended use in Biology and Medical Sciences, t...
Rocío Romero-Záliz, Coral del Val, J...
BIODATAMINING
2008
135views more  BIODATAMINING 2008»
13 years 6 months ago
Fast Gene Ontology based clustering for microarray experiments
Background: Analysis of a microarray experiment often results in a list of hundreds of diseaseassociated genes. In order to suggest common biological processes and functions for t...
Kristian Ovaska, Marko Laakso, Sampsa Hautaniemi