Sciweavers

50 search results - page 2 / 10
» Statistical Characterization of Protein Ensembles
Sort
View
JBCB
2010
123views more  JBCB 2010»
13 years 3 months ago
Characterizing the Space of interatomic Distance Distribution Functions Consistent with Solution Scattering Data
: Scattering of neutrons and x-rays from molecules in solution offers alternative approaches to the studying of a wide range of macromolecular structures in their solution state w...
Paritosh A. Kavathekar, Bruce A. Craig, Alan M. Fr...
ALGORITHMICA
2007
70views more  ALGORITHMICA 2007»
13 years 5 months ago
Sampling Conformation Space to Model Equilibrium Fluctuations in Proteins
This paper proposes the Protein Ensemble Method (PEM) to model equilibrium fluctuations in proteins where fragments of the protein polypeptide chain can move independently of one ...
Amarda Shehu, Cecilia Clementi, Lydia E. Kavraki
BMCBI
2005
119views more  BMCBI 2005»
13 years 5 months ago
The distance-profile representation and its application to detection of distantly related protein families
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Chin-Jen Ku, Golan Yona
BMCBI
2006
111views more  BMCBI 2006»
13 years 5 months ago
Development of an unbiased statistical method for the analysis of unigenic evolution
Background: Unigenic evolution is a powerful genetic strategy involving random mutagenesis of a single gene product to delineate functionally important domains of a protein. This ...
Colleen D. Behrsin, Chris J. Brandl, David W. Litc...
ICML
2006
IEEE
14 years 6 months ago
A graphical model for predicting protein molecular function
We present a simple statistical model of molecular function evolution to predict protein function. The model description encodes general knowledge of how molecular function evolve...
Barbara E. Engelhardt, Michael I. Jordan, Steven E...