30 search results - page 3 / 6 » Statistical distributions of optimal global alignment scores... |
BMCBI
2005
13 years 4 months ago
2005
Background: Profile-profile methods have been used for some years now to detect and align homologous proteins. The best such methods use information from the background distributi...
BMCBI
2005
13 years 4 months ago
2005
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
BMCBI
2005
13 years 4 months ago
2005
Background: We present a complete re-implementation of the segment-based approach to multiple protein alignment that contains a number of improvements compared to the previous ver...
CIKM
2008
Springer
13 years 7 months ago
2008
Springer
Background: Accurate estimation of statistical significance of a pairwise alignment is an important problem in sequence comparison. Recently, a comparative study of pairwise stati...
BMCBI
2010
13 years 5 months ago
2010
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...