311 search results - page 2 / 63 » Statistical significance in biological sequence analysis |
BMCBI
2004
13 years 5 months ago
2004
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
ALMOB
2007
13 years 5 months ago
2007
Background: The optimal score for ungapped local alignments of infinitely long random sequences is known to follow a Gumbel extreme value distribution. Less is known about the imp...
BMCBI
2007
2007
FUNC: a package for detecting significant associations between gene sets and ontological annotations
13 years 5 months ago
Background: Genome-wide expression, sequence and association studies typically yield large sets of gene candidates, which must then be further analysed and interpreted. Informatio...
BMCBI
2006
13 years 5 months ago
2006
Background: An alternative to standard approaches to uncover biologically meaningful structures in micro array data is to treat the data as a blind source separation (BSS) problem...
CIKM
2008
Springer
13 years 7 months ago
2008
Springer
Background: Accurate estimation of statistical significance of a pairwise alignment is an important problem in sequence comparison. Recently, a comparative study of pairwise stati...