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SAC
2008
ACM
13 years 3 months ago
Strangeness-based feature weighting and classification of gene expression profiles
Achieving high classification accuracy is a major challenge in the diagnosis of cancer types based on gene expression profiles. These profiles are notoriously noisy in that a larg...
Haifeng Shao, Bei Yu, Joseph H. Nadeau
BMCBI
2008
167views more  BMCBI 2008»
13 years 4 months ago
Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classificat
Background: Large-scale compilation of gene expression microarray datasets across diverse biological phenotypes provided a means of gathering a priori knowledge in the form of ide...
Michael Gormley, Aydin Tozeren
BMCBI
2007
173views more  BMCBI 2007»
13 years 4 months ago
Recursive Cluster Elimination (RCE) for classification and feature selection from gene expression data
Background: Classification studies using gene expression datasets are usually based on small numbers of samples and tens of thousands of genes. The selection of those genes that a...
Malik Yousef, Segun Jung, Louise C. Showe, Michael...
BMCBI
2007
140views more  BMCBI 2007»
13 years 4 months ago
Prediction potential of candidate biomarker sets identified and validated on gene expression data from multiple datasets
Background: Independently derived expression profiles of the same biological condition often have few genes in common. In this study, we created populations of expression profiles...
Michael Gormley, William Dampier, Adam Ertel, Bilg...
IJBRA
2007
97views more  IJBRA 2007»
13 years 4 months ago
Structural Risk Minimisation based gene expression profiling analysis
: For microarray based cancer classification, feature selection is a common method for improving classifier generalisation. Most wrapper methods use cross validation methods to eva...
Xue-wen Chen, Byron Gerlach, Dechang Chen, ZhenQiu...