8 search results - page 2 / 2 » Strategies for measuring evolutionary conservation of RNA se... |
BMCBI
2010
13 years 5 months ago
2010
Background: A widely used method to find conserved secondary structure in RNA is to first construct a multiple sequence alignment, and then fold the alignment, optimizing a score ...
BMCBI
2008
13 years 5 months ago
2008
Background: Alternative splicing is a major contributor to the diversity of eukaryotic transcriptomes and proteomes. Currently, large scale detection of alternative splicing using...
BMCBI
2006
13 years 4 months ago
2006
Background: Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein...