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BMCBI
2008
128views more  BMCBI 2008»
13 years 5 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson
BMCBI
2006
152views more  BMCBI 2006»
13 years 5 months ago
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...
BMCBI
2006
85views more  BMCBI 2006»
13 years 5 months ago
Quality control for terms and definitions in ontologies and taxonomies
Background: Ontologies and taxonomies are among the most important computational resources for molecular biology and bioinformatics. A series of recent papers has shown that the G...
Jacob Köhler, Katherine Munn, Alexander R&uum...
DM
2006
128views more  DM 2006»
13 years 5 months ago
Non-trivial t-designs without repeated blocks exist for all t
A computer package is being developed at Bayreuth for the generation and investigation of discrete structures. The package is a C and C++ class library of powerful algorithms endow...
Luc Teirlinck
TKDE
2002
166views more  TKDE 2002»
13 years 5 months ago
A Comprehensive Analytical Performance Model for Disk Devices under Random Workloads
Our goal with this paper is to contribute a common theoretical framework for studying the performance of disk-storage devices. Understanding the performance behavior of these devi...
Peter Triantafillou, Stavros Christodoulakis, Cost...