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CMSB
2006
Springer
13 years 8 months ago
Stronger Computational Modelling of Signalling Pathways Using Both Continuous and Discrete-State Methods
Abstract. Starting from a biochemical signalling pathway model expressed in a process algebra enriched with quantitative information we automatically derive both continuous-space a...
Muffy Calder, Adam Duguid, Stephen Gilmore, Jane H...
CMSB
2009
Springer
13 years 11 months ago
Probabilistic Approximations of Signaling Pathway Dynamics
Systems of ordinary differential equations (ODEs) are often used to model the dynamics of complex biological pathways. We construct a discrete state model as a probabilistic appro...
Bing Liu, P. S. Thiagarajan, David Hsu
CMSB
2008
Springer
13 years 6 months ago
A Model Checking Approach to the Parameter Estimation of Biochemical Pathways
Model checking has historically been an important tool to verify models of a wide variety of systems. Typically a model has to exhibit certain properties to be classed `acceptable&...
Robin Donaldson, David Gilbert
UAI
2004
13 years 6 months ago
Solving Factored MDPs with Continuous and Discrete Variables
Although many real-world stochastic planning problems are more naturally formulated by hybrid models with both discrete and continuous variables, current state-of-the-art methods ...
Carlos Guestrin, Milos Hauskrecht, Branislav Kveto...
ICPR
2004
IEEE
14 years 6 months ago
Morphology Analysis of Physiological Signals Using Hidden Markov Models
We describe a clustering algorithm based on continuous Hidden Markov Models (HMM) to automatically classify both electrocardiogram (ECG) and intracranial pressure (ICP) beats base...
Daniel Novák, Lenka Lhotská, David C...