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BMCBI
2007
96views more  BMCBI 2007»
13 years 5 months ago
Structure and function predictions of the Msa protein in Staphylococcus aureus
Background: Staphylococcus aureus is a human pathogen that causes a wide variety of lifethreatening infections using a large number of virulence factors. One of the major global r...
Vijayaraj Nagarajan, Mohamed O. Elasri
BMCBI
2005
116views more  BMCBI 2005»
13 years 5 months ago
SuperLigands - a database of ligand structures derived from the Protein Data Bank
Background: Currently, the PDB contains approximately 29,000 protein structures comprising over 70,000 experimentally determined three-dimensional structures of over 5,000 differe...
Elke Michalsky, Mathias Dunkel, Andrean Goede, Rob...
BMCBI
2005
108views more  BMCBI 2005»
13 years 5 months ago
The modeled structure of the RNA dependent RNA polymerase of GBV-C Virus suggests a role for motif E in Flaviviridae RNA polymer
Background: The Flaviviridae virus family includes major human and animal pathogens. The RNA dependent RNA polymerase (RdRp) plays a central role in the replication process, and t...
François Ferron, Cécile Bussetta, H&...
BMCBI
2008
121views more  BMCBI 2008»
13 years 5 months ago
BioSAVE: Display of scored annotation within a sequence context
Background: Visualization of sequence annotation is a common feature in many bioinformatics tools. For many applications it is desirable to restrict the display of such annotation...
Richard F. Pollock, Boris Adryan
BMCBI
2006
134views more  BMCBI 2006»
13 years 5 months ago
Application of machine learning in SNP discovery
Background: Single nucleotide polymorphisms (SNP) constitute more than 90% of the genetic variation, and hence can account for most trait differences among individuals in a given ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...