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BMCBI
2010
129views more  BMCBI 2010»
13 years 4 months ago
Detection of distant evolutionary relationships between protein families using theory of sequence profile-profile comparison
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...
Mindaugas Margelevicius, Ceslovas Venclovas
BMCBI
2011
12 years 11 months ago
PhyloSim - Monte Carlo simulation of sequence evolution in the R statistical computing environment
Background: The Monte Carlo simulation of sequence evolution is routinely used to assess the performance of phylogenetic inference methods and sequence alignment algorithms. Progr...
Botond Sipos, Tim Massingham, Gregory E. Jordan, N...
GECCO
2008
Springer
129views Optimization» more  GECCO 2008»
13 years 5 months ago
Fitness calculation approach for the switch-case construct in evolutionary testing
A well-designed fitness function is essential to the effectiveness and efficiency of evolutionary testing. Fitness function design has been researched extensively. For fitness ...
Yan Wang, Zhiwen Bai, Miao Zhang, Wen Du, Ying Qin...
BMCBI
2006
161views more  BMCBI 2006»
13 years 4 months ago
A method for rapid similarity analysis of RNA secondary structures
Background: Owing to the rapid expansion of RNA structure databases in recent years, efficient methods for structure comparison are in demand for function prediction and evolution...
Na Liu, Tianming Wang
BMCBI
2006
115views more  BMCBI 2006»
13 years 4 months ago
The accuracy of several multiple sequence alignment programs for proteins
Background: There have been many algorithms and software programs implemented for the inference of multiple sequence alignments of protein and DNA sequences. The "true" ...
Paulo A. S. Nuin, Zhouzhi Wang, Elisabeth R. M. Ti...