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» Structured Output Prediction of Anti-cancer Drug Activity
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BMCBI
2010
120views more  BMCBI 2010»
13 years 4 months ago
KiDoQ: using docking based energy scores to develop ligand based model for predicting antibacterials
Background: Identification of novel drug targets and their inhibitors is a major challenge in the field of drug designing and development. Diaminopimelic acid (DAP) pathway is a u...
Aarti Garg, Rupinder Tewari, Gajendra P. S. Raghav...
BIBM
2010
IEEE
277views Bioinformatics» more  BIBM 2010»
13 years 2 months ago
Accurate prediction of ATP-binding residues using sequence and sequence-derived structural descriptors
ATP is a ubiquitous nucleotide that provides energy for cellular activities, catalyzes chemical reactions, and is involved in cellular signaling. The knowledge of the ATPprotein in...
Ke Chen 0003, Marcin J. Mizianty, Lukasz A. Kurgan
EMNLP
2010
13 years 2 months ago
Confidence in Structured-Prediction Using Confidence-Weighted Models
Confidence-Weighted linear classifiers (CW) and its successors were shown to perform well on binary and multiclass NLP problems. In this paper we extend the CW approach for sequen...
Avihai Mejer, Koby Crammer
BMCBI
2011
12 years 8 months ago
GPCR-SSFE: A comprehensive database of G-protein-coupled receptor template predictions and homology models
Background: G protein-coupled receptors (GPCRs) transduce a wide variety of extracellular signals to within the cell and therefore have a key role in regulating cell activity and ...
Catherine L. Worth, Annika Kreuchwig, Gunnar Klein...
ISMB
1996
13 years 5 months ago
Refining Neural Network Predictions for Helical Transmembrane Proteins by Dynamic Programming
For transmembrane proteins experimental determina-tion of three-dimensional structure is problematic. However, membrane proteins have important impact for molecular biology in gen...
Burkhard Rost, Rita Casadio, Piero Fariselli