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» Structured Output Prediction of Anti-cancer Drug Activity
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JBCB
2010
138views more  JBCB 2010»
12 years 11 months ago
Hierarchical Classification of Gene Ontology Terms Using the Gostruct Method
Protein function prediction is an active area of research in bioinformatics. And yet, transfer of annotation on the basis of sequence or structural similarity remains widely used ...
Artem Sokolov, Asa Ben-Hur
BMCBI
2008
155views more  BMCBI 2008»
13 years 5 months ago
AMMOS: Automated Molecular Mechanics Optimization tool for in silico Screening
Background: Virtual or in silico ligand screening combined with other computational methods is one of the most promising methods to search for new lead compounds, thereby greatly ...
Tania Pencheva, David Lagorce, Ilza Pajeva, Bruno ...
BMCBI
2011
12 years 8 months ago
In-silico prediction of disorder content using hybrid sequence representation
Background: Intrinsically disordered proteins play important roles in various cellular activities and their prevalence was implicated in a number of human diseases. The knowledge ...
Marcin J. Mizianty, Tuo Zhang, Bin Xue, Yaoqi Zhou...
BMCBI
2007
181views more  BMCBI 2007»
13 years 5 months ago
ASMPKS: an analysis system for modular polyketide synthases
Background: Polyketides are secondary metabolites of microorganisms with diverse biological activities, including pharmacological functions such as antibiotic, antitumor and agroc...
Hongseok Tae, Eun-Bae Kong, Kiejung Park
CACM
1998
103views more  CACM 1998»
13 years 4 months ago
The Virtual Design Team
The long range goal of the “Virtual Design Team” (VDT) research program is to develop computational tools to analyze decision making and communication behavior and thereby to ...
John C. Kunz, Tore R. Christiansen, Geoff P. Cohen...